
Spotlight: Center for BRCA and Related Genes
Inherited mutations in BRCA1, BRCA2, and other BRCA-related DNA repair genes confer increased risk of multiple tumor types – particularly breast, ovarian, pancreatic, and prostate cancers. Moreover, it is now clear that many cancers can acquire mutations in the BRCA and other related DNA repair genes only in their tumor cells, even though the patient was not born with the genetic mutation.